BEGIN:VCALENDAR
VERSION:2.0
PRODID:icalendar-ruby
CALSCALE:GREGORIAN
X-WR-CALNAME:Organic/Inorganic/Materials Chemistry Seminar Series 
X-WR-TIMEZONE:Pacific Time (US & Canada)
BEGIN:VEVENT
DTSTAMP:20261007T102046Z
UID:tag:localist.com\,2008:EventInstance_45862776319312
DTSTART:20240315T220000Z
DTEND:20240315T230000Z
DESCRIPTION:Department of Chemistry and Biochemistry\n\nOrganic/Inorganic/M
 aterials Seminar Series\n\n \n\nProfessor Jeffrey Dick\, Purdue University
  \n\nHosted by CBGReAT\n\n \n\nDroplet Like It’s Hot: Understanding Curi
 ous Chemistry in Multiphase Microenvironments with Nanoelectrochemistry\n\
 nOver the past decade\, several reports have emerged demonstrating chemist
 ry depends on the reaction volume in which it is occurring. This surprisin
 g finding has been observed across fields of measurement\, from fluorimetr
 y to mass spectrometry. This talk will detail our group’s efforts in dev
 eloping new nanoelectrochemical tools to probe curious chemistry in sub-fe
 mtoliter volumes [1]. We will answer the question: Are biochemical reactio
 ns as studied in beakers representative of reactions presently occurring w
 ithin our cells? [2] In the pursuit of an answer\, we will show that the f
 amous Michaelis-Menten equation requires modification in confined volumes.
  We will demonstrate that electroactive molecules are spontaneously produc
 ed in suspended droplets. [3] The previous work [1-3] is performed on aque
 ous nanodroplets suspended in a non-aqueous phase. However\, many studies 
 detailing microdroplet curious chemistry come from droplets suspended in a
 ir\, where the liquid|air boundary is the dominant interface (as opposed t
 o the water|organic boundary). Electrochemistry in air is rather difficult
 . This difficulty comes from the strict requirement of needing two electro
 des to make an electrochemical measurement. We will go on a journey of dis
 covery through developing electrochemical measurement tools to probe react
 ivity in a bubble wall. [4] We have recently demonstrated that this experi
 ment allows the electrochemical interrogation of single micrometer-sized l
 iquid aerosol droplets\, where a majority of the interface is the liquid|a
 ir boundary. [5] This interface accelerates enzyme reactions beyond the wa
 ter|organic interface\, a truth of nature that has broad implications on t
 he genesis and propagation of life. \n\n\n[1] Lu\, S.\; Vannoy\, K. J.\; D
 ick\, J. E.*\; Long\, Y. T.* Multiphase Chemistry under Nanoconfinement: A
 n Electrochemical Perspective\, Journal of the American Chemical Society\,
  2023 145\, 25043 – 25055.\n[2] Vannoy\, K. J.\; Lee\, I.\; Sode\, K.\; 
 Dick\, J. E.* Electrochemical Quantification of Accelerated FADGDH Rates i
 n Aqueous Nanodroplets\, Proceedings of the National Academy of Sciences U
 SA\, 2021\, 118\, e2025726118. \n[3] Krushinski\, L. E.\; Dick\, J. E.* Di
 rect Electrochemical Evidence Suggests that Aqueous Microdroplets Spontane
 ously Produce Hydrogen Peroxide\, Proceedings of the National Academy of S
 ciences USA\, 2024\, Accepted\, DOI: doi.org/10.1073/pnas.2321064121 \n[4]
  Vannoy\, K. J.\; Tarolla\, N. E.\; Kauffmann\, P. J.\; Clark\, R. B.\; Di
 ck\, J. E.* Detecting Methamphetamine in Aerosols by Electroanalysis in a 
 Soap Bubble Wall\, Analytical Chemistry\, 2022\, 94\, 6311 – 6317. \n[5]
  Krushinski\, L. E.\; Vannoy\, K. J.\; Dick\, J. E.* Single Liquid Aerosol
  Microparticle Electrochemistry on a Suspended Ionic Liquid Film\, Small\,
  2024\, 2308637.
GEO:44.045653;-123.072531
LOCATION:Willamette Hall\, 110
SUMMARY:Organic/Inorganic/Materials Chemistry Seminar Series 
URL;VALUE=URI:https://calendar.uoregon.edu/event/organicinorganicmaterials-
 chemistry-seminar-series
CATEGORIES:Academic
CATEGORIES:Lectures & Presentations
CATEGORIES:Research
END:VEVENT
END:VCALENDAR